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Literature summary for 2.7.11.17 extracted from
- Age-related expression of calcium/calmodulin-dependent protein kinase II A in the hippocampus and cerebral cortex of SAMP8 mice is modulated by anti-Alzheimers disease drugs (2008), Neuroscience, 159, 308-315.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | in the cerebral cortex of SAMP8 mice, CaMKIIalpha mRNA expression increases significantly after 2 months of age | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| huperzine A | downregulates abnormally high expression of CaMKIIalpha | Mus musculus |  |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | dependent on | Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | P11798 | strain senescence-accelerated mouse prone/8 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cerebral cortex | - |
Mus musculus | - |
| hippocampus | - |
Mus musculus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| calcium/calmodulin-dependent protein kinase II-alpha | - |
Mus musculus |
| CaMKIIalpha | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| Calmodulin | dependent on | Mus musculus | |
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