Inhibitors | Comment | Organism | Structure |
---|---|---|---|
ARRKWQKTGHAVRAIGRLSS | calmodulin antagonist peptide, IC50: 33.3 nM in H2O, 10.6 nM in buffer containing 0.1% w/v Tween 80 | eukaryota | |
additional information | synthesis of peptides behaving as autoregulatory pseudosubstrates, determination of inhibitory potential, sequences of autoregulatory regions of the different enzyme forms, required sequence properties, overview | eukaryota |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | binding required for activity | eukaryota |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | eukaryota | - |
ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
eukaryota | - |
enzyme forms alpha, beta, gamma, delta | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | autophosphorylation at Ser19 | eukaryota |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | - |
eukaryota | ADP + a phosphoprotein | - |
? | |
additional information | substrate specificity | eukaryota | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Cam-II PK | - |
eukaryota |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
eukaryota | |
Calmodulin | binding required for activity | eukaryota |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | Ki values of the pseudosubstrates in nano- to micromolar range | eukaryota |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.0000333 | - |
calmodulin antagonist peptide, IC50: 33.3 nM in H2O, 10.6 nM in buffer containing 0.1% w/v Tween 80 | eukaryota | ARRKWQKTGHAVRAIGRLSS |