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Literature summary for 2.7.11.17 extracted from

  • Schanen, N.C.; Landreth, G.
    Isolation and characterization of microtubule-associated protein 2 (MAP2) kinase from rat brain (1992), Mol. Brain Res., 14, 43-50.
    View publication on PubMed
Search for more literature for 2.7.11.17

Inhibitors

Inhibitors Comment Organism Structure
additional information no inhibition by specific inhibitors of protein kinases A or C and Ca2+/calmodulin dependent protein kinase Rattus norvegicus
Protein kinase inhibitor H7 weak Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
additional information low abundance protein, analogous to kinase of growth factor stimulated cell lines Rattus norvegicus
-
-

Metals/Ions

Metals/Ions Comment Organism Structure
Ca2+ not Rattus norvegicus

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + histone H1 (best substrate) Rattus norvegicus ?
-
 ?
ATP + histone V-S Rattus norvegicus ?
-
 ?
ATP + microtubule-associated protein 2 i.e. MAP-2, preferred substrate Rattus norvegicus ADP + microtubule-associated protein 2 phosphate
-
 ?
ATP + myelin basic protein
-
 Rattus norvegicus ?
-
 ?
ATP + PC12 pheochromacytoma cell line protein substrate pp250
-
 Rattus norvegicus ?
-
 ?
ATP + tubulin
-
 Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
additional information
-
 pI: 4.9 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
Calmodulin not Rattus norvegicus