Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cell membrane | - |
Drosophila melanogaster | - |
- |
cell membrane | - |
Homo sapiens | - |
- |
cytoplasm | - |
Drosophila melanogaster | 5737 | - |
cytoplasm | - |
Homo sapiens | 5737 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Drosophila melanogaster | Gprk2 interacts with the Drosophila IkB homolog Cactus | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | - |
- |
- |
Drosophila melanogaster | - |
- |
- |
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HeLa cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Gprk2 interacts with the Drosophila IkB homolog Cactus | Drosophila melanogaster | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Gprk2 | - |
Drosophila melanogaster |
GRK5 | - |
Homo sapiens |
GRK5 | - |
Danio rerio |
General Information | Comment | Organism |
---|---|---|
malfunction | morpholino silencing of the zebrafish ortholog of Gprk2 in fish embryos causes impaired cytokine expression after Escherichia coli infection | Danio rerio |
malfunction | RNA silencing of GRK5 in HeLa cells impairs NF-kappaB reporter activity | Homo sapiens |
malfunction | using a genome-wide RNAi screen Grk2 is identified as a conserved regulator of NF-kappaB signaling | Drosophila melanogaster |