Cloned (Comment) | Organism |
---|---|
overexpression of the C-terminus of betaARK in ventricular cardiomyocytes and in the myocardium of rabbits suffering heart failure by adenoviral gene transfer, co-expression of N-terminal deletion mutant of phosducin, leading to increase in contractility of the cells due to inhibition of Gbetagamma subunits rather than to beta-adrenergic receptor resensitization, betaARK additionally stimulates cAMP production | Homo sapiens |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of betaARKct mutant comprising the C-terminus of the enzyme | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | betaARK enhances the contractility in heart myocardium via inhibition of Gbetagamma subunits | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
heart | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | betaARK enhances the contractility in heart myocardium via inhibition of Gbetagamma subunits | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
betaARK | - |
Homo sapiens |