Cloned (Comment) | Organism |
---|---|
beta-ARK 1 is stably overexpressed in HEK-293 cells | Bos taurus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Bos taurus | 5829 | - |
membrane | microsomal and plasma membrane, anchoring of beta-ARK to cellular membranes under basal conditions is independent of the availability of heterotrimeric G protein subunits, additional anchoring mechanisms, Gbetagamma subunits may play a role in agonist-mediated targeting of beta-ARK to the membrane in intact cells | Bos taurus | 16020 | - |
microsome | microsomal membranes | Bos taurus | - |
- |
additional information | subcellular distribution of beta-ARK 1 | Bos taurus | - |
- |
plasma membrane | - |
Bos taurus | 5886 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
80000 | - |
Western blot analysis | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | beta-ARK 1 is a key regulatory enzyme involved in the regulation of G protein-coupled receptors which associate with microsomal and plasma membranes | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
beta-ARK 1 | - |
Bos taurus | - |
enzyme exists in 2 subtypes: beta-ARK 1 and beta-ARK 2 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + beta-adrenergic receptor | - |
Bos taurus | ADP + phospho-beta-adrenergic receptor | - |
? | |
additional information | beta-ARK 1 is a key regulatory enzyme involved in the regulation of G protein-coupled receptors which associate with microsomal and plasma membranes | Bos taurus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Bos taurus |