Activating Compound | Comment | Organism | Structure |
---|---|---|---|
light | stimulates rhodopsin activation by phosphorylation | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of transgenic mouse photoreceptor cells overexpressing the human S opsin mutant K296E still show the trans-phosphorylation phenomenon and phosphorylation of nonactivated rhodopsin, overview | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Mus musculus | 16020 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + rhodopsin | Mus musculus | the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells | ADP + phosphorhodopsin | - |
? | |
additional information | Mus musculus | dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
ATP + rhodopsin = ADP + phosphorhodopsin | molecular mechanism of trans-phosphorylation | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
photoreceptor | - |
Mus musculus | - |
retina | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + rhodopsin | - |
Mus musculus | ADP + phosphorhodopsin | - |
? | |
ATP + rhodopsin | the enzyme phosphorylates activated rhodopsin, light causes phosphorylation of nonactivated rhodopsin in intact rod photoreceptor cells | Mus musculus | ADP + phosphorhodopsin | - |
? | |
ATP + S opsin | trans-phosphorylation is induced by activated rhodopsin | Mus musculus | ADP + phosphorylated S opsin | - |
? | |
additional information | dark-adapted retina rhodopsin is also phosphorylated in transgenic photoreceptor cells overexpressing the human S opsin mutant K296E | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | the enzyme belongs to the G-protein coupled receptor kinase family | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus |