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Literature summary for 2.7.11.14 extracted from

  • McCarthy, N.E.M.; Akhtar, M.
    Activation of rhodopsin kinase (2002), Biochem. J., 363, 359-364.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.14

Activating Compound

Activating Compound Comment Organism Structure
additional information activation of RK by metarhodopsin II and III, their phosphorylated derivatives, all the derivatives of opsin, which contain the Schiff base linkage with the all-trans-retinylidene moiety, but not opsin Ovis sp.
rhodopsin RK normally exists in an inactive resting state and is only activated following interaction with photoactivated rhodopsin Ovis sp.
rhodopsin metarhodopsin II and III, or their phosphorylated derivatives activate Ovis sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Ovis sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + rhodopsin Ovis sp.
-
 ADP + phosphorhodopsin
-
 ?

Organism

Organism UniProt Comment Textmining
Ovis sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 338-SKTETSQVAPA-348 peptide containing the last 11 amino acids of the C-terminal of bovine rhodopsin Ovis sp. ?
-
 ?
ATP + 338-SKTETSQVAPA-348 only in the presence of photoactivated rhodopsin, which activates RK for peptide phosphorylation, also activated by metarhodopsin III, but not by opsin, up to 60% of the rate with photoactivated rhodopsin, light-dependent phosphorylation Ovis sp. ?
-
 ?
ATP + rhodopsin
-
 Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin 4 mol phosphate/mol rhodopsin Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin substrates: metarhodopsin II and III Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin light-dependent phosphorylation Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin highly specific for photobleached rhodopsin Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin RK normally exists in an inactive resting state and is only activated following interaction with photoactivated rhodopsin Ovis sp. ADP + phosphorhodopsin
-
 ?
ATP + rhodopsin high-gain phosphorylation of rhodopsin Ovis sp. ADP + phosphorhodopsin
-
 ?
additional information not: apoprotein opsin Ovis sp. ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
20
-
 assay at Ovis sp.
37
-
 assay at Ovis sp.