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Literature summary for 2.7.11.13 extracted from

  • Raveh-Amit, H.; Hai, N.; Rotem-Dai, N.; Shahaf, G.; Gopas, J.; Livneh, E.
    Protein kinase Ceta activates NF-kappaB in response to camptothecin-induced DNA damage (2011), Biochem. Biophys. Res. Commun., 412, 313-317.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
MCF-7 cell
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Homo sapiens
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Synonyms

Synonyms Comment Organism
PKCeta
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Homo sapiens

General Information

General Information Comment Organism
physiological function PKCeta activates NF-kappaB in MCF-7 cells by activating the IkappaB kinase (IKK) and the degradation of IkappaB. PKCeta enhances the nuclear translocation and transactivation of NF-kappaB under non-stressed conditions and in response to the anticancer drug camptothecin Homo sapiens