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Literature summary for 2.7.11.12 extracted from

  • Mannai, S.; Bitri, L.; Thany, S.H.
    cGMP/cGMP-dependent protein kinase pathway modulates nicotine-induced currents through the activation of ?-bungarotoxin-insensitive nicotinic acetylcholine receptors from insect neurosecretory cells (2016), J. Neurochem., 137, 931-938.
    View publication on PubMed
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Inhibitors

Inhibitors Comment Organism Structure
KT5823 i.e. (8R,9S,11S)-(-)-9-methoxy-carbamyl-8-methyl-2,3,9,10-tetrahydro-8,11-epoxy-1H,8H,11H-2,7b,11a-trizadibenzo-(a,g)-cycloocta-(c,d,e)-trinden-1-one, potent and highly specific inhibitor Periplaneta americana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Periplaneta americana
-
 ADP + phosphorylated protein
-
 ?

Organism

Organism UniProt Comment Textmining
Periplaneta americana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron
-
 Periplaneta americana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
 Periplaneta americana ADP + phosphorylated protein
-
 ?

Synonyms

Synonyms Comment Organism
PKG
-
 Periplaneta americana

General Information

General Information Comment Organism
malfunction enzyme inhibition modulates nicotine-induced currents mediated by nicotinic acetylcholine receptor2 Periplaneta americana