Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cGMP | - |
Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | PKG exerts dual functional regulation of neuronal ATP-sensitive potassium channels in a sulfonylurea receptor subunit-dependent manner, which may provide new means of therapeutic intervention for manipulating neuronal excitability and/or survival | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
KT5823 | - |
Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
HEK-293 cell | - |
Homo sapiens | - |
SH-SY5Y cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + Kemptide | - |
Homo sapiens | ADP + Kemptide phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKG | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
cGMP | dependent | Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00023 | - |
- |
Homo sapiens | KT5823 |