Activating Compound | Comment | Organism | Structure |
---|---|---|---|
8-bromo-cGMP | 0.1 mM | Homo sapiens | |
8-bromo-cGMP | 0.1 mM | Rattus norvegicus | |
additional information | the activity of transient receptor potential channel 6 channels is markedly suppressed by PKG activation | Homo sapiens | |
additional information | the activity of transient receptor potential channel 6 channels is markedly suppressed by PKG activation | Rattus norvegicus | |
nitric oxide | - |
Homo sapiens | |
nitric oxide | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
DT3 | - |
Homo sapiens | |
DT3 | - |
Rattus norvegicus | |
KT-5823 | - |
Homo sapiens | |
KT-5823 | - |
Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
A7r5 cell | - |
Rattus norvegicus | - |
HEK-293 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + transient receptor potential channel 6 | PKG phosphorylation is reduced in transient receptor potential channel 6 mutant T69A | Homo sapiens | ADP + phosphorylated transient receptor potential channel 6 | - |
? | |
ATP + transient receptor potential channel 6 | PKG phosphorylation is reduced in transient receptor potential channel 6 mutant T69A | Rattus norvegicus | ADP + phosphorylated transient receptor potential channel 6 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
cGMP-protein kinase G | - |
Homo sapiens |
cGMP-protein kinase G | - |
Rattus norvegicus |
PKG Ialpha | - |
Homo sapiens |
PKG Ialpha | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
ATP | - |
Rattus norvegicus | |
cGMP | dependent | Homo sapiens | |
cGMP | dependent | Rattus norvegicus |