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Literature summary for 2.7.11.12 extracted from

  • Raizen, D.M.; Cullison, K.M.; Pack, A.I.; Sundaram, M.V.
    A novel gain-of-function mutant of the cyclic GMP-dependent protein kinase egl-4 affects multiple physiological processes in Caenorhabditis elegans (2006), Genetics, 173, 177-187.
    View publication on PubMedView publication on EuropePMC
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Activating Compound

Activating Compound Comment Organism Structure
cGMP
-
 Caenorhabditis elegans

Cloned(Commentary)

Cloned (Comment) Organism
gene egl-4, expression analysis of wild-type and mutant enzymes Caenorhabditis elegans

Protein Variants

Protein Variants Comment Organism
additional information construction of the gain-of-function mutant egl-4 of PKG, mutation causes increased normal gene activity although it is associated with a reduced EGL-4 protein level, multiple phenotypes of egl-4 dominant mutants, detailed analysis, overview, isolation of egl-4 loss-of-function mutations in cis to ad450sd and of extragenic suppressors of ad450sd, overview Caenorhabditis elegans

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
 Caenorhabditis elegans

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Caenorhabditis elegans PKG has an instructive signaling role to control many aspects of animal physiology ?
-
 ?

Organism

Organism UniProt Comment Textmining
Caenorhabditis elegans
-
 several strains
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information PKG has an instructive signaling role to control many aspects of animal physiology Caenorhabditis elegans ?
-
 ?
additional information structure-function relationship of PKG Caenorhabditis elegans ?
-
 ?

Subunits

Subunits Comment Organism
More structure-function relationship of PKG Caenorhabditis elegans

Synonyms

Synonyms Comment Organism
cyclic GMP-dependent protein kinase
-
 Caenorhabditis elegans
PKG
-
 Caenorhabditis elegans

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Caenorhabditis elegans