Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | complete enzyme inhibition inhibits pseudopod formation and cell migration | Homo sapiens | |
additional information | complete enzyme inhibition inhibits pseudopod formation and cell migration | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | the enzyme plays a paradoxical role in cell motility facilitating and inhibiting actin cytoskeletal dynamics and cell migration, overview, the enzyme is regulated in a subcellular space during cell migration, regulatory subunits RII are enriched in protrusive cellular structures and pseudopodia formed during chemotaxis, anchoring of PKA inhibits pseudopod formation and cell migration, regulation of the process overview | ? | - |
? | |
additional information | Rattus norvegicus | the enzyme plays a paradoxical role in cell motility facilitating and inhibiting actin cytoskeletal dynamics and cell migration, overview, the enzyme is regulated in a subcellular space during cell migration, regulatory subunits RII are enriched in protrusive cellular structures and pseudopodia formed during chemotaxis, anchoring of PKA inhibits pseudopod formation and cell migration, regulation of the process overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
REF-52 cell | embryonic fibroblast cell line | Rattus norvegicus | - |
WI-38 cell | fetal lung fibroblast-like cell line | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + protein tyrosine phosphatase | i.e. PTP, contains a PEST motif | Homo sapiens | ADP + phosphorylated protein tyrosine phosphatase | - |
? | |
ATP + protein tyrosine phosphatase | i.e. PTP, contains a PEST motif | Rattus norvegicus | ADP + phosphorylated protein tyrosine phosphatase | - |
? | |
ATP + VASP | i.e. vasodilator-stimulated phosphoprotein | Homo sapiens | ADP + phosphorylated VASP | - |
? | |
ATP + VASP | i.e. vasodilator-stimulated phosphoprotein | Rattus norvegicus | ADP + phosphorylated VASP | - |
? | |
additional information | the enzyme plays a paradoxical role in cell motility facilitating and inhibiting actin cytoskeletal dynamics and cell migration, overview, the enzyme is regulated in a subcellular space during cell migration, regulatory subunits RII are enriched in protrusive cellular structures and pseudopodia formed during chemotaxis, anchoring of PKA inhibits pseudopod formation and cell migration, regulation of the process overview | Homo sapiens | ? | - |
? | |
additional information | the enzyme plays a paradoxical role in cell motility facilitating and inhibiting actin cytoskeletal dynamics and cell migration, overview, the enzyme is regulated in a subcellular space during cell migration, regulatory subunits RII are enriched in protrusive cellular structures and pseudopodia formed during chemotaxis, anchoring of PKA inhibits pseudopod formation and cell migration, regulation of the process overview | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PKA | - |
Homo sapiens |
PKA | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
ATP | - |
Rattus norvegicus |