Application | Comment | Organism |
---|---|---|
molecular biology | tetrandrine suppresses LPS-induced astrocyte activation via modulating IKKs-IkappaBalpha-NF-kappaB signaling pathway | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
tetrandrine | a bis-benzylisoquinoline alkaloid isolated from the roots of Han-Fang-Ji (Stephania Tetrandra S Moore) effectively inhibits IKKs phosphorylation | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | - |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
astrocyte | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + IkappaBalpha | - |
Rattus norvegicus | ADP + phosphorylated-IkappaBalpha | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IkappaB kinase alpha | - |
Rattus norvegicus |
IKK | - |
Rattus norvegicus |