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Literature summary for 2.7.11.1 extracted from
- Akt activation by Ca2+/calmodulin-dependent protein kinase kinase 2 (CaMKK2) in ovarian cancer cells (2017), J. Biol. Chem., 292, 14188-14204 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Sf9 cells | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P31749 | - |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| phosphoprotein | CaMKK2 directly phosphorylates ans activates Akt at Thr308 independently of the PI3K/PDK1 pathway | Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AKT1 | - |
Homo sapiens |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | hyperactivation of Akt is associated with oncogenic changes in the growth, survival, and chemoresistance of cancer cells | Homo sapiens |
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Release 2023.1 (January 2023)
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