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Literature summary for 2.7.11.1 extracted from
- A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus (1993), Cell, 74, 743-756.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytoplasm | the cytoplasmic C-terminal portion of the enzyme carries an essential protein kinase activity | Saccharomyces cerevisiae | 5737 | - |
| membrane | a transmembrane enzyme | Saccharomyces cerevisiae | 16020 | - |
| microsome | glycosylated N-terminal portion is located inside microsomes | Saccharomyces cerevisiae | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + a protein | Saccharomyces cerevisiae | the enzyme is required for signaling from the ER to the nucleus | ADP + a phosphoprotein | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | P32361 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + a protein | the enzyme is required for signaling from the ER to the nucleus | Saccharomyces cerevisiae | ADP + a phosphoprotein | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Ern1p | - |
Saccharomyces cerevisiae |
| serine/threonine-protein kinase IRE1 precursor | - |
Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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