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Literature summary for 2.7.11.1 extracted from

  • Sato, N.; Arai, K.; Masai, H.
    Human and Xenopus cDNAs encoding budding yeast Cdc7-related kinases: in vitro phosphorylation of MCM subunits by a putative human homologue of Cdc7 (1997), EMBO J., 16, 4340-4351.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.11.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in COS7 cells Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm distributed diffusibly in cytoplasm in the mitotic phase Homo sapiens 5737
-
nucleus the enzyme is localized primarily in nuclei in interphase Homo sapiens 5634
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein Homo sapiens huCdc7 may regulate processes of DNA replication by modulating MCM functions ADP + a phosphoprotein
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens O00311
-
-

Source Tissue

Source Tissue Comment Organism Textmining
testis transcribed most abundantly in testis Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein huCdc7 may regulate processes of DNA replication by modulating MCM functions Homo sapiens ADP + a phosphoprotein
-
 ?
ATP + MCM2 wild-type huCdc7 protein expressed in COS7 cells phosphorylates MCM2 and MCM3 proteins in vitro Homo sapiens ADP + ?
-
 ?
ATP + MCM3 wild-type huCdc7 protein expressed in COS7 cells phosphorylates MCM2 and MCM3 proteins in vitro Homo sapiens ADP + ?
-
 ?

Synonyms

Synonyms Comment Organism
cell division cycle 7-related protein kinase
-
 Homo sapiens