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Literature summary for 2.7.11.1 extracted from

  • Oishi, I.; Sugiyama, S.; Otani, H.; Yamamura, H.; Nishida, Y.; Minami, Y.
    A novel Drosophila nuclear protein serine/threonine kinase expressed in the germline during its establishment (1998), Mech. Dev., 71, 49-63.
    View publication on PubMed

Localization

Localization Comment Organism GeneOntology No. Textmining
nucleus localized to the nuclei in a speckled pattern. Dmnk proteins become detectable in both somatic and germ line cell nuclei upon their arrival at the periplasm of the syncytial embryo, but then disappear from the somatic cell nuclei. Consistent with mRNA expression, Dmnk proteins in pole cell nuclei are sustained during gastrulation Drosophila melanogaster 5634
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Drosophila melanogaster enzyme plays a role in germ line establishment ?
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?

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster O61267
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Source Tissue

Source Tissue Comment Organism Textmining
embryo at early cleavage-stages Dmnk transcripts are transiently present throughout the embryo, but become restricted to the posterior pole and then to the newly-formed primordial germ cells by the blastoderm stage. The transcripts are sustained in the pole cells during gastrulation Drosophila melanogaster
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oocyte
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Drosophila melanogaster
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information enzyme plays a role in germ line establishment Drosophila melanogaster ?
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?

Synonyms

Synonyms Comment Organism
ovarian-specific serine/threonine-protein kinase Lok
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Drosophila melanogaster