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Literature summary for 2.7.11.1 extracted from

  • Webster, M.K.; Goya, L.; Ge, Y.; Maiyar, A.C.; Firestone, G.L.
    Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum (1993), Mol. Cell. Biol., 13, 2031-2040.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
49000
-
x * 49000 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element ?
-
?
additional information Rattus norvegicus the enzyme is highly regulated at the transcriptional level by glucocorticoid hormones ?
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q06226
-
-

Source Tissue

Source Tissue Comment Organism Textmining
cell culture Con8.hd6 rat mammary tumor cell line Rattus norvegicus
-
lung high activity Rattus norvegicus
-
ovary high activity Rattus norvegicus
-
thymus high activity Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element Rattus norvegicus ?
-
?
additional information the enzyme is highly regulated at the transcriptional level by glucocorticoid hormones Rattus norvegicus ?
-
?

Subunits

Subunits Comment Organism
? x * 49000 Rattus norvegicus

Synonyms

Synonyms Comment Organism
serine/threonine-protein kinase Sgk
-
Rattus norvegicus