Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element | ? | - |
? | |
additional information | Rattus norvegicus | induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | Q06226 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | the cells which strongly express the sgk gene are in the deep layers of the cortex and in the corpus callosum. It is likely that the sgk transcript is expressed by oligodendrocytes after brain injury. Neurons in layers I and II of the cortex, lateroposterior and laterodorsal thalamic nucleus, and ventral posterolateral and posteromedial thalamic nucleus strongly express sgk mRNA at postnatal day 1 and day 7, but these neurons show no expression in fetal or adult brain. Induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain | Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme is transcriptionally regulated by serum and glucocorticoids in mammary epithelial cells, hormone-regulated protein kinase gene with a functionally defined p53 promoter recognition element | Rattus norvegicus | ? | - |
? | |
additional information | induction of sgk gene may be associated with a series of axonal regenerations after brain injury, and in addition, the sgk gene may also play important roles in the development of particular groups of neurons in the postnatal brain | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
serine/threonine-protein kinase Sgk | - |
Rattus norvegicus |