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Literature summary for 2.7.10.2 extracted from

  • Zhang, X.; Simerly, C.; Hartnett, C.; Schatten, G.; Smithgall, T.E.
    Src-family tyrosine kinase activities are essential for differentiation of human embryonic stem cells (2014), Stem Cell Res., 13, 379-389.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Inhibitors

Inhibitors Comment Organism Structure
A-419259
-
 Homo sapiens
PP2
-
 Homo sapiens
SKI-1
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a [protein]-L-tyrosine Homo sapiens
-
 ADP + a [protein]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
embryonic stem cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a [protein]-L-tyrosine
-
 Homo sapiens ADP + a [protein]-L-tyrosine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
C-SRC
-
 Homo sapiens
C-YES
-
 Homo sapiens
Fyn
-
 Homo sapiens
HCK
-
 Homo sapiens
Lck
-
 Homo sapiens
Lyn
-
 Homo sapiens
SFK
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens Lck expression levels drop dramatically as a function of embryoid body differentiation down
Homo sapiens c-Src and Fyn show a modest increase in expression as a function of stem cell differentiation up