Literature summary for 2.7.10.2 extracted from

Marcotte, D.; Liu, Y.; Arduini, R.; Hession, C.; Miatkowski, K.; Wildes, C.; Cullen, P.; Hong, V.; Hopkins, B.; Mertsching, E.; Jenkins, T.; Romanowski, M.; Baker, D.; Silvian, L.
Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases (2010), Protein Sci., 19, 429-439.

Search for more literature for 2.7.10.2

Cloned(Commentary)

Cloned (Comment)	Organism
-	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
1.94 A resolution crystal structure of the Bruton's tyrosine kinase Y551E mutant kinase domain bound to Dasatinib and a 1.6 A resolution crystal structure of the unphosphorylated human wild-type kinase domain bound to 4-amino-5-(4-phenoxyphenyl)-7H-pyrrolospyrimidin-7-yl-cyclopentane	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
Y551E	in complex with inhibitor dasatinib, crystal structure	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
32643	-	x * 32641.6 calculated, x * 32643, mass spectrometry	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q06187	Btk	-

Subunits

Subunits	Comment	Organism
?	x * 32641.6 calculated, x * 32643, mass spectrometry	Homo sapiens

Synonyms

Synonyms	Comment	Organism
Bruton's tyrosine kinase	-	Homo sapiens
Btk	-	Homo sapiens

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Release 2023.1 (January 2023)