Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q14289 | PYK2 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | G-protein coupled receptor PAC1 regulates the tyrosine phosphorylation of isoform PYK2 in NCI-H838 nonsmall cell lung cancer cells. PYK2 phosphorylation is dependent upon Ca2+. The ability of PAC1 to regulate PYK2 is dependent on phospholipase and Src, and partially dependent on proteinkinase C | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
Pyk2 | - |
Homo sapiens |