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Literature summary for 2.7.10.2 extracted from

  • Tsuruno, S.; Kawaguchi, S.Y.; Hirano, T.
    Src-family protein tyrosine kinase negatively regulates cerebellar long-term depression (2008), Neurosci. Res., 61, 329-332.
    View publication on PubMed
Search for more literature for 2.7.10.2

Application

Application Comment Organism
medicine Src-family protein tyrosine kinases are involved in the regulation of the long-term depression, LTD, induction Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
4-amino-5-(4-chlorophenyl)-7-(t-butyl)pyrazolo[3,4-d]pyrimidine PP2 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + [protein]-L-tyrosine Rattus norvegicus
-
 ADP + [protein]-L-tyrosine phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus Q9WUD9 Wistar rat
-

Source Tissue

Source Tissue Comment Organism Textmining
neuron Purkinje neuron Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + [protein]-L-tyrosine
-
 Rattus norvegicus ADP + [protein]-L-tyrosine phosphate
-
 ?

Synonyms

Synonyms Comment Organism
Src-family protein kinase
-
 Rattus norvegicus