Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | Btk activation is induced by FcgammaR signaling, activation requires binding to phosphatidylinositol 3,4,5-trisphosphate | Mus musculus | |
additional information | Tec activation is induced by FcgammaR signaling, activation requires binding to phosphatidylinositol 3,4,5-trisphosphate | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
LFM-A13 | - |
Mus musculus | |
siRNA | - |
Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [protein]-L-tyrosine | Mus musculus | - |
ADP + [protein]-L-tyrosine phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Mus musculus | P24604 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
phosphoprotein | phosphorylation by other kinases and autophosphorylation | Mus musculus |
phosphoprotein | phosphorylation by other kinases and autophosphorylation at Tyr223 of Btk | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
peritoneal macrophage | - |
Mus musculus | - |
RAW-264.7 cell | - |
Mus musculus | - |
splenocyte | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + [protein]-L-tyrosine | - |
Mus musculus | ADP + [protein]-L-tyrosine phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Brutons tyrosine kinase | - |
Mus musculus |
Btk | - |
Mus musculus |
Tec kinase | - |
Mus musculus |