Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | brain-derived neurotrophic factor BDNF induces the association and colocalization of TrkB with the lipid raft-resident protein Fyn, in situ study | Mus musculus | |
additional information | brain-derived neurotrophic factor BDNF induces the association and colocalization of TrkB with the lipid raft-resident protein Fyn, in situ study | Rattus norvegicus |
Protein Variants | Comment | Organism |
---|---|---|
additional information | construction of Fyn brain knockout mice, brain-derived neurotrophic factor BDNF-induced TrkB, Akt, and PLCgamma phosphorylation is affected in Fyn knock-out neurons, phenotype, overview | Mus musculus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | - |
Mus musculus | |
Mg2+ | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Rattus norvegicus | tyrosine kinase Fyn determines the specific localization of TrkB brain-derived neurotrophic factor, BDNF, receptor in to intracellular lipid rafts in cortical and hippocampal membranes, this process is critically dependent on the tyrosine kinase Fyn, overview, role for lipid rafts in neurotrophin signaling | ? | - |
? | |
additional information | Mus musculus | tyrosine kinase Fyn determines the specific localization of TrkB brain-derived neurotrophic factor, BDNF, receptor to intracellular lipid rafts in cortical and hippocampal membranes, this process is critically dependent on the tyrosine kinase Fyn, overview, role for lipid rafts in neurotrophin signaling | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
brain | corticohippocampal region | Mus musculus | - |
brain cortex | - |
Mus musculus | - |
hippocampus | - |
Mus musculus | - |
neuron | - |
Mus musculus | - |
neuron | primary cortical neuron culture | Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | tyrosine kinase Fyn determines the specific localization of TrkB brain-derived neurotrophic factor, BDNF, receptor in to intracellular lipid rafts in cortical and hippocampal membranes, this process is critically dependent on the tyrosine kinase Fyn, overview, role for lipid rafts in neurotrophin signaling | Rattus norvegicus | ? | - |
? | |
additional information | tyrosine kinase Fyn determines the specific localization of TrkB brain-derived neurotrophic factor, BDNF, receptor to intracellular lipid rafts in cortical and hippocampal membranes, this process is critically dependent on the tyrosine kinase Fyn, overview, role for lipid rafts in neurotrophin signaling | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Fyn | - |
Mus musculus |
Fyn | - |
Rattus norvegicus |
tyrosine kinase Fyn | - |
Mus musculus |
tyrosine kinase Fyn | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Mus musculus | |
ATP | - |
Rattus norvegicus |