Protein Variants | Comment | Organism |
---|---|---|
additional information | siRNA Syk knockout, overview, preparation of a stem loop rat aerosolized Syk antisense-liposome complexes leading to downregulation of airway inflammatory responses, overview | Rattus norvegicus |
additional information | Syk silencing in TNP1-cells by siRNA interference leads to inhibition of lipopolysaccharide-induced responses in the cells, and to downregulation of IL-6 and IL-8 release, overview | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Homo sapiens | Syk protein tyrosine kinase is involved in lipopolysaccharide-induced responses and intracellular signaling leading to release of pro-inflammatory mediators in macrophages, overview | ? | - |
? | |
additional information | Rattus norvegicus | Syk protein tyrosine kinase is involved in lipopolysaccharide-induced responses and intracellular signaling leading to release of pro-inflammatory mediators in macrophages, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Rattus norvegicus | - |
male sprague-dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leukocyte | - |
Homo sapiens | - |
leukocyte | - |
Rattus norvegicus | - |
macrophage | - |
Homo sapiens | - |
macrophage | peritoneal and alveolar | Rattus norvegicus | - |
mast cell | - |
Homo sapiens | - |
mast cell | - |
Rattus norvegicus | - |
THP-1 cell | a myelocytic cell line | Homo sapiens | - |
trachea | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Syk protein tyrosine kinase is involved in lipopolysaccharide-induced responses and intracellular signaling leading to release of pro-inflammatory mediators in macrophages, overview | Homo sapiens | ? | - |
? | |
additional information | Syk protein tyrosine kinase is involved in lipopolysaccharide-induced responses and intracellular signaling leading to release of pro-inflammatory mediators in macrophages, overview | Rattus norvegicus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Syk | - |
Homo sapiens |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | - |
Homo sapiens | |
ATP | - |
Rattus norvegicus |