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Literature summary for 2.7.10.2 extracted from

  • Zarbock, A.; Lowell, C.A.; Ley, K.
    Spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1 (2007), Immunity, 26, 773-783.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.7.10.2

Protein Variants

Protein Variants Comment Organism
additional information E-selectin-induced alpha(L)beta(2) integrin-mediated rolling is abolished in syk-/- mice bone marrow, neutrophil recruitment in a thioglycollate-induced peritonitis model is almost completely inhibited, overview Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1, neutrophil activation pathways, overview ?
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
bone marrow
-
 Mus musculus
-
neutrophil primary Mus musculus
-
spleen
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information spleen tyrosine kinase Syk is necessary for E-selectin-induced alpha(L)beta(2) integrin-mediated rolling on intercellular adhesion molecule-1, neutrophil activation pathways, overview Mus musculus ?
-
 ?

Synonyms

Synonyms Comment Organism
Spleen tyrosine kinase
-
 Mus musculus
Syk
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
ATP
-
 Mus musculus