Protein Variants | Comment | Organism |
---|---|---|
additional information | mutant lacking the C-terminal noncatalytic region has about a 10fold higher kinase activity in vitro and, when expressed in HeLa cells, induces punctate actin aggregates in the cytoplasm and unusual condensation and fragmentation of nuclei, followed by apoptosis | Rattus norvegicus |
additional information | mutant lacking the C-terminal noncatalytic region has about a 10fold higher kinase activity in vitro and, when expressed in HeLa cells, induces punctate actin aggregates in the cytoplasm and unusual condensation and fragmentation of nuclei, followed by apoptosis | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
nucleus | localized mainly in | Rattus norvegicus | 5634 | - |
nucleus | localized mainly in | Homo sapiens | 5634 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | Rattus norvegicus | the enzyme induces formation of actin stress fibers and focal adhesions | ADP + a phosphoprotein | - |
? | |
ATP + a protein | Homo sapiens | the enzyme induces formation of actin stress fibers and focal adhesions | ADP + a phosphoprotein | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q96S53 | - |
- |
Rattus norvegicus | Q924U5 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Sertoli cell | predominant expression in | Rattus norvegicus | - |
Sertoli cell | predominant expression in | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + a protein | the enzyme induces formation of actin stress fibers and focal adhesions | Rattus norvegicus | ADP + a phosphoprotein | - |
? | |
ATP + a protein | the enzyme induces formation of actin stress fibers and focal adhesions | Homo sapiens | ADP + a phosphoprotein | - |
? | |
ATP + cofilin | phosphorylation specifically at Ser-3 | Rattus norvegicus | ADP + phosphorylated cofilin | - |
? | |
ATP + cofilin | phosphorylation specifically at Ser-3 | Homo sapiens | ADP + phosphorylated cofilin | - |
? |
Synonyms | Comment | Organism |
---|---|---|
TESK2 | - |
Rattus norvegicus |
TESK2 | - |
Homo sapiens |
testis-specific protein kinase 2 | - |
Rattus norvegicus |
testis-specific protein kinase 2 | - |
Homo sapiens |