Literature summary for 2.7.10.2 extracted from

Bozzi, F.; Lefranc, G.; Villa, A.; Badolato, R.; Schumacher, R.F.; Khalil, G.; Loiselet, J.; Bresciani, S.; O'Shea, J.J.; Vezzoni, P.; Notarangelo, L.D.; Candotti, F.
Molecular and biochemical characterization of JAK3 deficiency in a patient with severe combined immunodeficiency over 20 years after bone marrow transplantation: implications for treatment (1998), Br. J. Haematol., 102, 1363-1366.

Search for more literature for 2.7.10.2

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Homo sapiens	JAK3 deficiency in a patient with severe combined immunodeficiency over 20 years after bone marrow transplantation: persistence of genetically and biochemically defective autologous B cells, associated with reconstitution of cellular and humoral immunity, suggests that integrity of the gammac-JAK3 signalling pathway is not strictly required for immunoglobulin production	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P52333	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	JAK3 deficiency in a patient with severe combined immunodeficiency over 20 years after bone marrow transplantation: persistence of genetically and biochemically defective autologous B cells, associated with reconstitution of cellular and humoral immunity, suggests that integrity of the gammac-JAK3 signalling pathway is not strictly required for immunoglobulin production	Homo sapiens	?	-	?

Synonyms

Synonyms	Comment	Organism
tyrosine-protein kinase JAK3	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)