Application | Comment | Organism |
---|---|---|
medicine | tyrosine phosphorylation events mediated by aberrant activation of RTK pathways are proven to be involved in the development of several diseases including cancer. 70% of tyrosine phosphorylation events are conserved in human orthologs and paralogs | Homo sapiens |
additional information | around 38% tyrosine phosphorylation events from Drosophila RTK proteins conserved on 185 human proteins are confirmed in vivo tyrosine phosphorylation events | Drosophila melanogaster |
Cloned (Comment) | Organism |
---|---|
Drosophila S2 cells stably transfected with human ErbB1 | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | P09208 | - |
- |
Homo sapiens | P35916 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
S2 cell | - |
Drosophila melanogaster | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | ErbB1 receptor shows three phosphorylation sites (Y1110, Y1172 and Y1192) | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EGF receptor | - |
Homo sapiens |
EGF RTK | - |
Homo sapiens |
ERBB1 | - |
Homo sapiens |
InR | - |
Drosophila melanogaster |
insulin RTK | - |
Drosophila melanogaster |
insulin-like receptor | - |
Drosophila melanogaster |
receptor tyrosine kinase | - |
Drosophila melanogaster |
receptor tyrosine kinase | - |
Homo sapiens |
RTK | - |
Drosophila melanogaster |
RTK | - |
Homo sapiens |