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Literature summary for 2.7.10.1 extracted from

  • MacKintosh, C.; MacKintosh, R.W.
    Inhibitors of protein kinases and phosphatases (1994), Trends Biochem. Sci., 19, 444-448.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
genistein protein tyrosine kinase inhibitor eukaryota
additional information no inhibition by daidzein eukaryota
N6-Dimethylaminopurine unspecific inhibitor of protein kinases eukaryota
PD-153035 synthetic inhibitor, highly specific for the epidermal growth factor receptor eukaryota
staurosporine unspecific inhibitor of protein kinases eukaryota

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
eukaryota 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+
-
eukaryota

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + a protein eukaryota
-
ADP + a phosphoprotein
-
?

Organism

Organism UniProt Comment Textmining
eukaryota
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + a protein
-
eukaryota ADP + a phosphoprotein
-
?

Synonyms

Synonyms Comment Organism
EGF receptor tyrosine kinase
-
eukaryota
epidermal growth factor receptor
-
eukaryota
insulin receptor
-
eukaryota
platelet-derived growth factor receptor
-
eukaryota

Cofactor

Cofactor Comment Organism Structure
ATP
-
eukaryota