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BRENDA support

Literature summary for 2.7.1.95 extracted from

  • Doi, O.; Miyamoto, M.; Tanaka, N.; Umezawa, H.
    Inactivation and phosphorylation of kanamycin by drug-resistant Staphylococcus aureus (1968), Appl. Microbiol., 16, 1282-1284.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Staphylococcus aureus
-
drug-resistant strain B295
-
Staphylococcus aureus
-
multiple drug-resistant strain B294
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + kanamycin no activity with streptomycin Staphylococcus aureus ADP + kanamycin 3'-phosphate
-
?
ATP + neomycin
-
Staphylococcus aureus ADP + neomyin phosphate
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
35 37 assay at Staphylococcus aureus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7 7.5
-
Staphylococcus aureus

pH Range

pH Minimum pH Maximum Comment Organism
6 8 approx. half-maximal activity at pH 6.0 and pH 8.0 Staphylococcus aureus