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Literature summary for 2.7.1.91 extracted from
- Inhibition of sphingosine kinase in vitro and in platelets. Implications for signal transduction pathways (1992), J. Biol. Chem., 267, 3154-3159.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D(+)threo-Sphinganine | - |
Rattus norvegicus |  |
| dihydrosphingosine | L-erythro-, L-threo- and D-threo-isomer | Rattus norvegicus | |
| L(-)threo-Sphinganine | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + sphinganine | Rattus norvegicus | D-erythro-sphinganine, sphingosine metabolism | ADP + sphinganine 1-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + sphinganine | D-erythro-sphinganine, sphingosine metabolism | Rattus norvegicus | ADP + sphinganine 1-phosphate | - |
? | |
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