Inhibitors | Comment | Organism | Structure |
---|---|---|---|
D(+)threo-Sphinganine | - |
Homo sapiens | |
EDTA | - |
Homo sapiens | |
L(-)erythro-Sphinganine | - |
Homo sapiens | |
L(-)threo-Sphinganine | - |
Homo sapiens | |
N-ethylmaleimide | - |
Homo sapiens | |
p-chloromercuribenzoate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.072 | - |
D-(+)-erythro-sphinganine | - |
Homo sapiens | |
1 | - |
L-(-)-threo-sphinganine | - |
Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytoplasm | - |
Homo sapiens | 5737 | - |
cytoplasm | - |
Sus scrofa | 5737 | - |
soluble | - |
Homo sapiens | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | stimulation at concentration equimolar to ATP | Homo sapiens | |
Mn2+ | stimulation at concentration equimolar to ATP | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Sus scrofa | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
thrombocyte | - |
Homo sapiens | - |
thrombocyte | - |
Sus scrofa | - |
Storage Stability | Organism |
---|---|
-18°C, stable for at least 3 weeks | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-(+)-erythro-sphinganine | - |
Homo sapiens | ADP + D-(+)-erythro-sphinganine 1-phosphate | - |
? | |
ATP + L-(-)-threo-sphinganine | - |
Homo sapiens | ADP + L-(-)-threo-sphinganine 1-phosphate | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7 | - |
- |
Homo sapiens |
7 | - |
- |
Sus scrofa |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6 | 8.5 | pH 6: about 55% of maximum activity, pH 8.5: about 40% of maximum activity | Homo sapiens |