BRENDA - Enzyme Database
show all sequences of 2.7.1.81

Guanosine triphosphate: 5-hydroxylysine phosphotransferase in rat kidney cortex

Chang, A.Y.; Enzyme 22, 230-234 (1977)

Data extracted from this reference:

Inhibitors
Inhibitors
Commentary
Organism
Structure
choline
-
Rattus norvegicus
D-Lysine
-
Rattus norvegicus
D-ornithine
-
Rattus norvegicus
ethanolamine
-
Rattus norvegicus
L-lysine
-
Rattus norvegicus
L-ornithine
-
Rattus norvegicus
additional information
no inhibition by serine, threonine, and hydroxyproline
Rattus norvegicus
KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0238
-
5-hydroxy-lysine
-
Rattus norvegicus
Metals/Ions
Metals/Ions
Commentary
Organism
Structure
Mg2+
required
Rattus norvegicus
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
GTP + 5-hydroxy-L-lysine
Rattus norvegicus
-
GDP + O-phosphohydroxy-L-lysine
-
Rattus norvegicus
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Rattus norvegicus
-
-
-
Purification (Commentary)
Commentary
Organism
partial
Rattus norvegicus
Source Tissue
Source Tissue
Commentary
Organism
Textmining
kidney
cortex
Rattus norvegicus
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
GTP + 5-hydroxy-L-lysine
-
642035
Rattus norvegicus
GDP + O-phosphohydroxy-L-lysine
-
642035
Rattus norvegicus
?
additional information
no activity with threonine, serine, or hydroxyproline
642035
Rattus norvegicus
?
-
-
-
-
pH Optimum
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Rattus norvegicus
Inhibitors (protein specific)
Inhibitors
Commentary
Organism
Structure
choline
-
Rattus norvegicus
D-Lysine
-
Rattus norvegicus
D-ornithine
-
Rattus norvegicus
ethanolamine
-
Rattus norvegicus
L-lysine
-
Rattus norvegicus
L-ornithine
-
Rattus norvegicus
additional information
no inhibition by serine, threonine, and hydroxyproline
Rattus norvegicus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
0.0238
-
5-hydroxy-lysine
-
Rattus norvegicus
Metals/Ions (protein specific)
Metals/Ions
Commentary
Organism
Structure
Mg2+
required
Rattus norvegicus
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
GTP + 5-hydroxy-L-lysine
Rattus norvegicus
-
GDP + O-phosphohydroxy-L-lysine
-
Rattus norvegicus
?
Purification (Commentary) (protein specific)
Commentary
Organism
partial
Rattus norvegicus
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
kidney
cortex
Rattus norvegicus
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
GTP + 5-hydroxy-L-lysine
-
642035
Rattus norvegicus
GDP + O-phosphohydroxy-L-lysine
-
642035
Rattus norvegicus
?
additional information
no activity with threonine, serine, or hydroxyproline
642035
Rattus norvegicus
?
-
-
-
-
pH Optimum (protein specific)
pH Optimum Minimum
pH Optimum Maximum
Commentary
Organism
8
-
-
Rattus norvegicus
Other publictions for EC 2.7.1.81
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
720057
Veiga-da-Cunha
Molecular identification of hy ...
Homo sapiens
J. Biol. Chem.
287
7246-7255
2012
-
-
1
-
-
-
-
4
-
-
-
-
-
2
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
4
-
-
-
-
-
-
-
-
-
1
-
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
4
4
642035
Chang
Guanosine triphosphate: 5-hydr ...
Rattus norvegicus
Enzyme
22
230-234
1977
-
-
-
-
-
-
7
1
-
1
-
1
-
1
-
-
1
-
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
1
-
1
-
1
-
-
-
1
-
1
-
-
2
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
642034
Hiles
The partial purification and p ...
Bos taurus, Cebus albifrons, Chlorocebus aethiops, Gallus gallus, Mus musculus, no activity in Homo sapiens, Oryctolagus cuniculus, Rattus norvegicus
J. Biol. Chem.
247
646-651
1972
-
-
-
-
-
-
16
2
-
8
-
1
-
9
-
-
1
-
-
12
1
1
3
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-
-
-
-
-
-
16
-
2
-
8
-
1
-
-
-
1
-
12
1
1
3
-
1
-
-
-
1
1
-
-
-
-
-
-
-
-