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Literature summary for 2.7.1.77 extracted from

  • Shin, I.S.; Wataya, Y.
    Characterization of nucleoside phosphotransferase from Leishmania tropica (1995), Nucleosides Nucleotides, 14, 13-22.
No PubMed abstract available
Search for more literature for 2.7.1.77

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0057
-
 2'-deoxyinosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0059
-
 Inosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0059
-
 2'-deoxyadenosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0061
-
 adenosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0063
-
 2'-deoxyguanosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0064
-
 guanosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0066
-
 3'-fluoroinosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0071
-
 3'-deoxyadenosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0084
-
 3'-deoxyinosine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.014
-
 thymidine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0153
-
 2'-deoxycytidine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0167
-
 uridine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica
0.0169
-
 cytidine pH 7.5, 37°C, reaction with 4-nitrophenyl phosphate Leishmania tropica

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Leishmania tropica 5737
-
membrane
-
 Leishmania tropica 16020
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40000
-
 gel filtration Leishmania tropica

Organism

Organism UniProt Comment Textmining
Leishmania tropica
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
130
-
-
 Leishmania tropica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-nitrophenyl phosphate + 2'-deoxyadenosine
-
 Leishmania tropica 2'-deoxyadenosine 5'-phosphate + 2'-deoxyadenosine 3'-phosphate + 4-nitrophenol
-
 ?
4-nitrophenyl phosphate + 2'-deoxycytidine
-
 Leishmania tropica 4-nitrophenol + 2'-deoxycytidine 5'-phosphate
-
 ?
4-nitrophenyl phosphate + 2'-deoxyguanosine
-
 Leishmania tropica 4-nitrophenol + 2'-deoxyguanosine 5'-phosphate
-
 ?
4-nitrophenyl phosphate + 2'-deoxyinosine
-
 Leishmania tropica 4-nitrophenol + 2'-deoxyinosine 5'-phosphate
-
 ?
4-nitrophenyl phosphate + 3'-deoxyadenosine
-
 Leishmania tropica 4-nitrophenol + 3'-deoxyadenosine 5'-phosphate
-
 ?
4-nitrophenyl phosphate + 3'-deoxyinosine
-
 Leishmania tropica 4-nitrophenol + 3'-deoxyinosine 5'-phosphate
-
 ?
4-nitrophenyl phosphate + 3'-fluoroinosine
-
 Leishmania tropica 4-nitrophenol + 3'-fluoro-IMP
-
 ?
4-nitrophenyl phosphate + adenosine
-
 Leishmania tropica 5'-AMP + 4-nitrophenol
-
 ?
4-nitrophenyl phosphate + cytidine
-
 Leishmania tropica 4-nitrophenol + CMP
-
 ?
4-nitrophenyl phosphate + guanosine
-
 Leishmania tropica 4-nitrophenol + GMP
-
 ?
4-nitrophenyl phosphate + inosine
-
 Leishmania tropica 4-nitrophenol + IMP
-
 ?
4-nitrophenyl phosphate + thymidine
-
 Leishmania tropica 4-nitrophenol + TMP
-
 ?
4-nitrophenyl phosphate + uridine
-
 Leishmania tropica 4-nitrophenol + 5'-UMP
-
 ?