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Literature summary for 2.7.1.68 extracted from
- Phosphatidylinositol 4-phosphate 5-kinase alpha negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells (2013), Exp. Mol. Med., 45, e16.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | Rattus norvegicus | - |
ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-12 cell | - |
Rattus norvegicus | - |
| pheochromocytoma cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
Rattus norvegicus | ADP + 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phosphatidylinositol 4-phosphate 5-kinase alpha | - |
Rattus norvegicus |
| PIP5Kalpha | - |
Rattus norvegicus |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | enzyme PIP5Kalpha acts as a negative regulator of nerve growth factor-induced neurite outgrowth by inhibiting phosphatidylinositol 3-kinase/Akt signaling pathway in PC-12 cells | Rattus norvegicus |
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Release 2023.1 (January 2023)
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