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Literature summary for 2.7.1.67 extracted from

  • Ryder, P.V.; Vistein, R.; Gokhale, A.; Seaman, M.N.; Puthenveedu, M.A.; Faundez, V.
    The WASH complex, an endosomal Arp2/3 activator, interacts with the Hermansky-Pudlak syndrome complex BLOC-1 and its cargo phosphatidylinositol-4-kinase type IIalpha (2013), Mol. Biol. Cell, 24, 2269-2284.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol Homo sapiens
-
 ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
HEK-293T cell
-
 Homo sapiens
-
SHSY-5Y cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + 1-phosphatidyl-1D-myo-inositol
-
 Homo sapiens ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate
-
 ?

Synonyms

Synonyms Comment Organism
phosphatidylinositol-4-kinase type IIalpha
-
 Homo sapiens
PI4KIIalpha
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme interacts with peroxiredoxin-1, Nedd4-1, and vesicle-mediated transport proteins such as clathrin heavy chain and the pallidin subunit of BLOC-1 Homo sapiens