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Literature summary for 2.7.1.67 extracted from
- Interaction of neuronal calcium sensor-1 and ADP-ribosylation factor 1 allows bidirectional control of phosphatidylinositol 4-kinase beta and trans-Golgi network-plasma membrane traffic (2005), J. Biol. Chem., 280, 6047-6054.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol | Rattus norvegicus | neuronal calcium sensor-1 and the GTPase ARF1 are localized to the Golgi complex and regulate phosphatidylinositol 4-kinase IIIbeta. Spatial and temporal control of phosphatidylinositol 4-phosphate levels through activation of phosphatidylinositol 4-kinase IIIbeta is important for the recruitment of trafficking complexes to the trans-Golgi network and vesicular traffic from this organelle | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-12 cell | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 1-phosphatidyl-1D-myo-inositol | - |
Rattus norvegicus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
| ATP + 1-phosphatidyl-1D-myo-inositol | neuronal calcium sensor-1 and the GTPase ARF1 are localized to the Golgi complex and regulate phosphatidylinositol 4-kinase IIIbeta. Spatial and temporal control of phosphatidylinositol 4-phosphate levels through activation of phosphatidylinositol 4-kinase IIIbeta is important for the recruitment of trafficking complexes to the trans-Golgi network and vesicular traffic from this organelle | Rattus norvegicus | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| phosphatidylinositol 4-kinase beta | - |
Rattus norvegicus |
| phosphatidylinositol 4-kinase IIIbeta | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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