Inhibitors | Comment | Organism | Structure |
---|---|---|---|
adenosine | IC50: 0.07 mM. 1 mM, 93% inhibition | Sus scrofa | |
ADP | IC50: 0.12 mM. 1 mM, 92% inhibition | Sus scrofa | |
AMP | 1 mM, 48% inhibition | Sus scrofa | |
Ca2+ | inhibits Mg2+-stimulated activity, IC50: 0.4 mM | Sus scrofa | |
deoxycholate | 10 mM, 35% inhibition | Sus scrofa | |
GDP | 1 mM, 27% inhibition | Sus scrofa | |
GMP | 1 mM, 20% inhibition | Sus scrofa | |
GTP | 1 mM, 24% inhibition | Sus scrofa | |
guanosine | 1 mM, 50% inhibition | Sus scrofa | |
Lubrol Px | 1%, 72% inhibition | Sus scrofa | |
NEM | 0.1 mM, 42% inhibition | Sus scrofa | |
PCMB | 0.1 mM, 98% inhibition | Sus scrofa | |
phosphatidylethanolamine | 0.1 mM, 24% inhibition | Sus scrofa | |
phosphatidylglycerol | 0.1 mM, 63% inhibition | Sus scrofa | |
phosphatidylserine | 0.1 mM, 33% inhibition | Sus scrofa | |
quercetin | IC50: 0.1 mM | Sus scrofa | |
Sodium mersalyl | 0.1 mM, 78% inhibition | Sus scrofa | |
Triton X-100 | 0.2%, 11% inhibition | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.06 | - |
ATP | pH 7.5, 30°C | Sus scrofa | |
0.12 | - |
phosphatidylinositol | pH 7.5, 30°C | Sus scrofa |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Sus scrofa | - |
- |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Co2+ | divalent metal ions stimulate in decreasing order of efficiency: Mg2+, Fe2+, Mn2+, Fe3+, Co2+ | Sus scrofa | |
Fe2+ | divalent metal ions stimulate in decreasing order of efficiency: Mg2+, Fe2+, Mn2+, Fe3+, Co2+ | Sus scrofa | |
Fe3+ | divalent metal ions stimulate in decreasing order of efficiency: Mg2+, Fe2+, Mn2+, Fe3+, Co2+ | Sus scrofa | |
Mg2+ | divalent metal ions stimulate in decreasing order of efficiency: Mg2+, Fe2+, Mn2+, Fe3+, Co2+ | Sus scrofa | |
Mn2+ | divalent metal ions stimulate in decreasing order of efficiency: Mg2+, Fe2+, Mn2+, Fe3+, Co2+ | Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
55000 | - |
x * 55000, SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
8.824 | - |
- |
Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 1-phosphatidyl-1D-myo-inositol | - |
Sus scrofa | ADP + 1-phosphatidyl-1D-myo-inositol 4-phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 55000, SDS-PAGE | Sus scrofa |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.07 | - |
IC50: 0.07 mM. 1 mM, 93% inhibition | Sus scrofa | adenosine | |
0.1 | - |
IC50: 0.1 mM | Sus scrofa | quercetin | |
0.12 | - |
IC50: 0.12 mM. 1 mM, 92% inhibition | Sus scrofa | ADP | |
0.4 | - |
inhibits Mg2+-stimulated activity, IC50: 0.4 mM | Sus scrofa | Ca2+ |