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Literature summary for 2.7.1.60 extracted from

  • Amsili, S.; Zer, H.; Hinderlich, S.; Krause, S.; Becker-Cohen, M.; MacArthur, D.G.; North, K.N.; Mitrani-Rosenbaum, S.
    UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) binds to alpha-actinin 1: novel pathways in skeletal muscle? (2008), PLoS ONE, 3, e2477.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine no siginificant difference in the binding kinetics of alpha-activin 1 with either wild-type or mutant UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase involved in hereditary inclusion body myopathy Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in 293T cell Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9Y223 patients with hereditary inclusion body myopathy
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Subunits

Subunits Comment Organism
More bifunctional UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase interacts with alpha-actinin 1, the non-muscle form of alpha-actinin, which is expressed in skeletal muscle Homo sapiens