Literature summary for 2.7.1.40 extracted from

Benjaphokee, S.; Koedrith, P.; Auesukaree, C.; Asvarak, T.; Sugiyama, M.; Kaneko, Y.; Boonchird, C.; Harashima, S.
CDC19 encoding pyruvate kinase is important for high-temperature tolerance in Saccharomyces cerevisiae (2012), New Biotechnol., 29, 166-176.

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Cloned(Commentary)

Cloned (Comment)	Organism
gene CDC19 or HTG2, DNA and amino acid sequence determination and analysis, genotyping	Saccharomyces cerevisiae

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of Htg- host strains carrying only one htg allele by repeatedly back crossing Htg- segregants from a hybrid between HB8-3A(Htg+) and BY4742(Htg-) to the Htg+ strain (HB8-3A). Three Htg strains with the desired genotype, designated HC1-5D, HE6-8D and HE120-12A, are successfully constructed by the repeated back crossing process, phenotypes, overview. The Htg+ CDC19-C allele leads to an increase in trehalose accumulation under heat stress conditions. Strains containing a single copy of the CDC19-C and CDC19-BY allele in the HE6-8D background exhibit increased trehalose accumulation under heat stress conditions. Nevertheless, replacement with a single copy of CDC19-C in the HE6-8D background does not contribute to a further increase in trehalose accumulation as compared with the HE6-8D strain carrying the Htg- CDC19-BY allele	Saccharomyces cerevisiae

Organism

Organism	UniProt	Comment	Textmining
Saccharomyces cerevisiae	-	diverse strains, overview. Gene CDC19, i.e. HTG2	-

General Information

General Information	Comment	Organism
metabolism	CDC19 or HTG2 is involved in the phenotype of high-temperature growth	Saccharomyces cerevisiae

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Release 2023.1 (January 2023)