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Literature summary for 2.7.1.40 extracted from
- Interrelation between the inhibition of glycolytic flux by silibinin and the lowering of mitochondrial ROS production in perifused rat hepatocytes (2008), Life Sci., 82, 1070-1076.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| silibinin | inhibitory to pyruvate kinase, resulting in dose-dependently reduced glycolysis from carbohydrates and a fall in ATP-toADP ratio, together with an increase in lactate-to-pyruvate ratio in perifused hepatocyte | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| hepatocyte | - |
Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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