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Literature summary for 2.7.1.4 extracted from
- Characterization of hexokinase and fructokinase from suspension-cultured Catharanthus roseus cells (1988), Z. Naturforsch. C, 43, 827-834.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ADP | - |
Catharanthus roseus |  |
| AMP | - |
Catharanthus roseus | |
| UDP | - |
Catharanthus roseus | |
| UMP | - |
Catharanthus roseus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.05 | - |
ATP | with D-fructose as cosubstrate, pH 7.4, 30°C | Catharanthus roseus | |
| 0.13 | - |
D-fructose | with UTP as cosubstrate, pH 7.4, 30°C | Catharanthus roseus | |
| 0.15 | - |
UTP | with D-fructose as cosubstrate, pH 7.4, 30°C | Catharanthus roseus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | can partially replace Mg2+ or Mn2+ in activation | Catharanthus roseus | |
| Mg2+ | Mg2+ or Mn2+ required | Catharanthus roseus | |
| Mn2+ | Mn2+ or Mg2+ required | Catharanthus roseus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose | Catharanthus roseus | - |
ADP + D-fructose 6-phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Catharanthus roseus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Catharanthus roseus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Catharanthus roseus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Catharanthus roseus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + D-fructose | - |
Catharanthus roseus | ADP + D-fructose 6-phosphate | - |
? | |
| ATP + D-fructose | specific for fructose | Catharanthus roseus | ADP + D-fructose 6-phosphate | - |
? | |
| CTP + D-fructose | higher activity than with ATP | Catharanthus roseus | CDP + D-fructose 6-phosphate | - |
? | |
| additional information | no substrate: D-glucose | Catharanthus roseus | ? | - |
? | |
| UTP + D-fructose | higher activity than with ATP | Catharanthus roseus | UDP + D-fructose 6-phosphate | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.2 | - |
- |
Catharanthus roseus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6 | 8.5 | pH 6: about 55% of activity maximum, pH 8.5: about 35% of activity maximum | Catharanthus roseus |
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