Cloned (Comment) | Organism |
---|---|
- |
Mycobacterium tuberculosis |
Crystallization (Comment) | Organism |
---|---|
complexes of the enzyme with guanosine-5'-[(beta,gamma)-methyleno]triphosphate and pantothenate, GDP and phosphopantothenate, GDP, GDP and pantothenate, 5'-adenylyl (beta,gamma-methylene)diphosphonate, and guanosine-5'-[(beta,gamma)-methyleno]triphosphate, hanging drop vapor diffusion method, using 1.4-1.8 M trisodium citrate, 0.05-0.1 M sodium acetate, and 10% (v/v) glycerol at pH 6.5 | Mycobacterium tuberculosis |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.616 | - |
ATP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis | |
668 | - |
GTP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Mycobacterium tuberculosis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + (R)-pantothenate | - |
Mycobacterium tuberculosis | ADP + (R)-4'-phosphopantothenate | - |
? | |
GTP + (R)-pantothenate | - |
Mycobacterium tuberculosis | GDP + (R)-4'-phosphopantothenate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
PanK | - |
Mycobacterium tuberculosis |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.052 | - |
ATP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis | |
0.064 | - |
GTP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis |
kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.084 | - |
ATP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis | |
0.095 | - |
GTP | in citrate buffer, pH 6.5, temperature not specified in the publication | Mycobacterium tuberculosis |