Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose | Heterocephalus glaber | fructose enters glycolytic metabolism after phosphorylation by ketohexokinase and is converted to fructose-1-phosphate. Fructose-driven glycolytic respiration in Heterocephalus glaber tissues avoids feedback inhibition of glycolysis via phosphofructokinase, allowing continued glycolytic flux independent of cellular energy status and supporting viability | ADP + D-fructose 1-phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Heterocephalus glaber | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Heterocephalus glaber | - |
heart | - |
Heterocephalus glaber | - |
liver | - |
Heterocephalus glaber | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + D-fructose | - |
Heterocephalus glaber | ADP + D-fructose 1-phosphate | - |
? | |
ATP + D-fructose | fructose enters glycolytic metabolism after phosphorylation by ketohexokinase and is converted to fructose-1-phosphate. Fructose-driven glycolytic respiration in Heterocephalus glaber tissues avoids feedback inhibition of glycolysis via phosphofructokinase, allowing continued glycolytic flux independent of cellular energy status and supporting viability | Heterocephalus glaber | ADP + D-fructose 1-phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
KHK | - |
Heterocephalus glaber |
Khk-A | less efficient KHK-A isoform | Heterocephalus glaber |
Khk-C | fructose selective KHK-C isoform | Heterocephalus glaber |
General Information | Comment | Organism |
---|---|---|
metabolism | fructose-driven glycolytic respiration in Heterocephalus glaber tissues avoids feedback inhibition of glycolysis via phosphofructokinase, allowing continued glycolytic flux independent of cellular energy status and supporting viability | Heterocephalus glaber |