Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
32730 | - |
2-D gel analysis | Homo sapiens |
32730 | - |
theoretical | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P50053 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
renal cell carcinoma cell | represent the most prevalent cancer of the kidney. The mean ketohexokinase activity in the renal cell carcinoma tissue samples is approximately 1.4fold lower than that in their normal kidney tissue. Ketohexokinase activity is approximately 1.5fold lower in pT3 renal cell carcinoma tissue than that in pT1 renal cell carcinoma tissue. The enzyme activity of tumor in histological grade 3 is 1.8fold lower than for grade 1 tumor(reaction mixture activity assay: acid-treated supernatant (100 microl) containing 10 mM MgCl2, 50 mM TrisHCl, pH 7.4, 10 mM ATP, 50 mM N-acetyl-D-glucosamine, 10 mM D[UL-14C]fructose and water, at 37°C). The expression level of ketohexokinase mRNA is reduced two- to eightfold in nearly all the clear cell renal cell carcinoma tissue samples compared with normal kidney, except for one renal cell carcinoma sample. | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
fructokinase | ketohexokinase | Homo sapiens |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Homo sapiens | 2-D gel analysis | - |
5.6 |
Homo sapiens | calculated from amino acid sequence | - |
5.7 |