Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | the DhaR transcription factor stimulates the transcription of the dhaKLM operon from a sigma70 promotor and autorepresses expression of DhaR | Escherichia coli |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + glycerone | Escherichia coli | regulation involving de-/phosphorylation, and the 3 subunits with ADP and transcription factor DhaR, overview | pyruvate + glycerone phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P76015 | subunit DhaK | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
phosphoenolpyruvate + glycerone | - |
Escherichia coli | pyruvate + glycerone phosphate | i.e. dihydroxyacetone phosphate | ? | |
phosphoenolpyruvate + glycerone | regulation involving de-/phosphorylation, and the 3 subunits with ADP and transcription factor DhaR, overview | Escherichia coli | pyruvate + glycerone phosphate | - |
? |
Subunits | Comment | Organism |
---|---|---|
trimer | enzyme exists of 3 subunit DhaK, DhaM, and DhaL: DhaK contains the dihydroxyacetone phosphate binding site, DhaL contains ADP as cofactor for phosphate double displacement from DhaM to dihydroxyacetone phosphate, and DhaM provides a phospho-histidine relay between phosphoenolpyruvate and DhaL-ADP | Escherichia coli |
Synonyms | Comment | Organism |
---|---|---|
DHA kinase | - |
Escherichia coli |
dihydroxyacetone kinase | - |
Escherichia coli |
More | dihydroxyacetoe phosphate kinases exist in 2 different groups, one utilizing ATP as phosphate donor, the other utilizing phosphoenolpyrivate | Escherichia coli |
phosphoenolpyruvate carbohydrate phosphotransferase | - |
Escherichia coli |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
ATP | dependent on | Escherichia coli |